dna

In much of the developing world, goats are essential for survival and are highly valued for their meat, milk and hides. So it should come as no surprise that Agricultural Research Service (ARS) scientists and academic and industry colleagues, working with DNA from a domestic goat, used new technologies to develop a vastly improved and relatively inexpensive reference goat genome. This information will serve as a kind of instruction manual for scientists showing them how to use the same technologies to lower the cost of developing improved livestock genomes.

When most people think of forests, science isn’t the first thing that comes to mind, but, perhaps, it should. That’s because the U.S. Forest Service Research and Development program oversees projects across many science disciplines including forestry, genetics, wildlife, forest products and wildfire.

And the agency has been using this science to deliver returns on investments for stakeholders, industry partners, and the public.

When a little brown bat discovered near North Bend, Washington, in March tested positive for White-nose Syndrome or WNS, scientists had a lot of questions.

The bat was found nearly 1,300 miles from the nearest confirmed case of WNS in eastern North America, so the most pressing question was about the strain of fungus causing this disease: was this a known strain of the WNS-fungus, was this an entirely new strain from elsewhere in the world, or was this the same clone of fungus that has been spreading throughout the eastern United States since 2006?

The U.S. Forest Service has a long history as a leader in conservation genetics, and this recently took an exciting step forward with the launch of the National Genomics Center for Wildlife and Fish Conservation.

The Forest Service’s wildlife genetics lab, which has been central to the Rocky Mountain Research Station’s conservation genetics program since 1998, has been reorganized and renamed to better reflect the scope of its work nationwide. The Center is a leading edge facility for advanced genomics research, nationally recognized, and works extensively with states, tribes, universities and private groups to address the management issues of over 60 fish and wildlife species.

This post is part of the Science Tuesday feature series on the USDA blog. Check back each week as we showcase stories and news from the USDA’s rich science and research portfolio.

The idea that around 80 percent of human DNA is “junk” DNA with no real purpose never sat well with scientists.  So in 2003, researchers funded by the U.S. National Institutes of Health started working on a project called ENCODE, which was designed to study the role of non-coding “junk” DNA in genetic expression and to define basic functional units in the human genome.

USDA’s Agricultural Research Service (ARS) scientists are spearheading a parallel project called AgENCODE, which takes a similar approach to exploring the mechanics of DNA regulation in key livestock species. “We can identify 70 to 90 percent (or more) of the DNA coding elements in animal genomes, but we don’t know much at all about the non-coding elements,” says ARS National Program Leader Jeffrey Silverstein, who is helping to organize the AgENCODE effort. “We think many of these non-coding segments regulate gene activity, and we need to understand how these segments affect the expression of an animal’s physical traits, which is very important in breeding.”